DPCstruct | MC12935

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)149 ± 16 aa
Standard deviation of domain lengths15.98
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.61
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)40.32
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D6AGI2 26-156 LIASGDTRQFLWQLMTEKNTPLINEILLRIKQHPDFPDWRIKKKLPKYFLARQIAELKNNYPFEGQPSRFYASVNKIISYIYKSWFE…
A0A1E5QY38 1-147 MTQITIQCRLIASADTRQFLWMLMSQKNTPLINEILTRIRENPDFSQWEEKGKLPKNFISQQIAELKNDSCFQGQPSRFYASVGKII…
A0A6G3Z6W1 14-157 None
A0A1Z4HHQ0 12-166 None
A0YWR6 5-164 None
A0A2T1D8B6 1-191 None
A0A0D6ACB2 12-148 None
A0A7Y3TUB6 18-168 None
A0A846A9U0 1-153 None
B7JWD4 12-168 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.