DPCstruct | MC1293

Metacluster Properties and Pfam Annotations

Number of structural domains2
Mean domain length (aa)103 ± 7 aa
Standard deviation of domain lengths6.50
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score94.58
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)23.80
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K1A6H3 1-109 VLENVFKGEYTSWAAFKKAMYKERIDQLTKLKPITIEYELKNPNSTKKVTIRSYAEMQQLMDAAVAEDVRNITNATSRVEASWVNLL…
A0A7X2Y1V4 1-96 FIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKSYSTFEELQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQT…

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.