DPCstruct | MC12927

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)258 ± 47 aa
Standard deviation of domain lengths47.18
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.70
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)20.26
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C3YZP7 426-702 MSDHFHQLQINFNSWAKDPQSLMAGEPLFPTVQAKQDAVFKSLFHEQDEELRTLTCQALKYIMEEFMEVTDRMLKDYLPGGLFHQPS…
A0A6J8A5V4 2-157 EGITMWTQNHTANWLESLDEAHREQDLRQAREDSREQCQRYVERLADIRQQRQKALAMKREKKEAKEQRDRTKKEKLTQKLQEVGGL…
A0A401H4J4 49-359 None
A0A4Y9XVL9 3-247 None
A0A1I8I9B5 247-513 None
A0A1D3RPN1 2-253 None
A0A0C9V2I8 33-309 None
A0A0D0D1N7 127-390 None
A0A8B6EUL1 415-687 None
C3ZKV2 658-975 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.