DPCstruct | MC12925

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)158 ± 11 aa
Standard deviation of domain lengths10.68
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score78.77
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)88.07
Pfam Score100.00
Assigned Pfam label(s) PF10148

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A803Y955 84-239 MSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLMKRNLKPAD…
C3YV32 1-132 MAALRSGAQEGDDTDFLTKEAELKKEAQLALAMAKPMAQMQMEVEKQNRKKSPVADVVAATPSMAVISENLKRRKLKQRDLMNMSPG…
A0A6J3DEB7 180-335 None
A0A6P3RQK5 101-269 None
A0A670I2D3 320-500 None
A0A212CIP4 1-154 None
A0A3Q2QUL2 447-615 None
A0A6B0QTJ8 335-488 None
A0A6J2L0V1 302-457 None
A0A1A8QDT7 564-718 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.