DPCstruct | MC12912

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)70 ± 3 aa
Standard deviation of domain lengths2.76
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score80.78
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)62.73
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4HRK2 59-134 IADLPIELIELLEKIIIELSPFNDNKNLQNLLPLTAVCADKGKVVGYINKLQNYDYMEIAKIATEHGLFEEALTIY
A0A0S3SWD0 1-75 MTADLPHELIELLEKIVLHNSAFSGNFNLQNILILTAIKADPFRVMDYINRLDNFDGHAVGEMAIEAQLYGTNTC
A0A7J0E7A0 199-268 None
A0A819NSB9 795-862 None
Q10161 995-1061 None
A0A4Y9ZVK1 51-123 None
A0A7J6VZ10 310-379 None
A0A7J7MRW0 254-320 None
A0A7J7LRR7 224-293 None
A0A7J6W2W8 46-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.