DPCstruct | MC12905

Metacluster Properties and Pfam Annotations

Number of structural domains447
Mean domain length (aa)307 ± 79 aa
Standard deviation of domain lengths79.43
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.43
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)15.03
Pfam Score78.62
Assigned Pfam label(s) CL0126- PF01984- CL0209- CL0020- CL0512

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7HCM4 395-650 None
H2YTT0 325-597 None
E8N5A6 23-311 None
A0A6V7VL90 8-263 None
A0A2R7WH54 380-661 None
G0MW90 27-340 None
E9HG26 283-635 None
A0A7G2ETQ4 345-686 None
A0A3M7PND4 699-1227 None
A0A3M7PGZ9 192-555 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.