DPCstruct | MC12905

Metacluster Properties and Pfam Annotations

Number of structural domains447
Mean domain length (aa)307 ± 79 aa
Standard deviation of domain lengths79.43
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.43
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)15.03
Pfam Score78.62
Assigned Pfam label(s) CL0126- PF01984- CL0209- CL0020- CL0512

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0WKW6 86-465 None
A0A212ERH4 36-484 None
A0A3D4ED35 26-382 None
A0A7K3XFM2 26-230 None
A0A812KIM6 619-997 None
A0A1E5MEZ6 568-873 None
A0A812HZC4 82-439 None
A0A7W5UPI5 10-237 None
A0A484K4H5 16-394 None
A0A261XV01 2-340 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.