DPCstruct | MC12905

Metacluster Properties and Pfam Annotations

Number of structural domains447
Mean domain length (aa)307 ± 79 aa
Standard deviation of domain lengths79.43
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.43
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)15.03
Pfam Score78.62
Assigned Pfam label(s) CL0126- PF01984- CL0209- CL0020- CL0512

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V5PM48 5-330 AWLAAGVRQTPDAVIRALDMGGDEIIFPVNRVAASAGGWGDYPRAIVWAFLERGMQPTGLEAVLASDVPVGAGMSSSAAVEMAFAYA…
A0A090TH18 4-251 SVVVYAPASIGNVSVGFDVLGAAVSPVDGTLLGDCVEVRLGDKPFDLATKGSFVDKLPSDPKENIVYDCWKVYARELDKKGVTLKPV…
A0A7R9KFB9 22-322 None
A0A7J6L8Q7 916-1191 None
A0A819XFH6 23-454 None
A0A0A0DXN0 3-218 None
I1CMZ8 42-325 None
I1CD02 11-323 None
A0A226F6X6 532-891 None
A0A0D9VNM4 911-1250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.