DPCstruct | MC12886

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)230 ± 43 aa
Standard deviation of domain lengths43.24
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score68.09
Mean fraction of residues predicted as intrinsically disordered0.71
Mean length-normalized TM-Score0.24
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)21.99
Pfam Score96.27
Assigned Pfam label(s) CL0361- CL0449

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V1IY08 6-224 QRNKGYALLQKMGWKAGQGLGVKEEGVKEPIQVNEATDTRGLGKKTQEDQYIREVGRKRKTTDGERIAQETSEEREARESRVRKRQA…
A0A1R1PU31 3-210 LAEVKVKQRIGVDPRNLNWGNDKDKFGYKLMQKMGWKEGKGLGANESGMTDSLKVRLKLNNHGIGANKKSIENWMESSGDFEAVLAR…
A0A6J1PDJ7 1-214 None
A0A6V7TPF0 1-147 None
A0A2P6NTG4 36-221 None
A0A6U3RUZ0 19-223 None
R7U3A2 2-237 None
A0A835XM77 1-286 None
B4DVU2 1-184 None
E2C7C0 1-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.