DPCstruct | MC12878

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)71 ± 8 aa
Standard deviation of domain lengths8.36
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score82.62
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)38.47
Pfam Score100.00
Assigned Pfam label(s) CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F1YR61 38-121 None
A0A2S6VT26 3-71 None
A0A022PCA3 2-62 None
A0A7U3EB84 2-64 None
A0A1I5DY35 1-54 None
A0A327Q3S2 60-125 None
J2KFW2 20-91 None
A0A7C3QE90 18-94 None
W1IRG7 2-67 None
A0A2N3B9K6 11-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.