DPCstruct | MC12858

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)115 ± 7 aa
Standard deviation of domain lengths6.59
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score90.97
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)29.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U2NJ23 26-143 RPLREEAMTEMQQLVMELMDDRAEGRPKWKSTTTDLVEMIDDVYALGDVKDARGCDLTFSYMVQAVCRRLVKPVPRNPRSYAYRARM…
A0A133YZL6 51-167 QASAFALRQRILTRMSHDLQWLIAQPKGSVKWTGTQRDLVEMANLVWMQRTIVDEQGCPYCRRALVRRAFAAVGQPVPVNIERVVMR…
A0A134BHI4 14-136 None
L1MYE2 20-138 None
G1WDY5 2-115 None
F9D5V4 30-147 None
D1QVL8 1-108 None
A0A2U0UIL0 21-126 None
F0H7C3 77-200 None
A0A355XVX4 8-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.