DPCstruct | MC12853

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)77 ± 11 aa
Standard deviation of domain lengths10.95
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score78.90
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)53.66
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9A613 3-74 LEPFMHQVGGHSSMMCLDNFTVCKPLIERELRFYESLPDVMRPFTAECKGVTEVDCREDEKGYIALTAVPRN
Q7T0Q8 1-74 MSPAFGAMEVEHYAKGVLLEPFLHQVGGHSCVLRFNDKTICKPLIQREHLFYETLPAEIRKFTPQYKGTFSLLS
A0A286XMX4 1-72 None
A0A2P8Y9N9 1-62 None
A0A5E4CG61 51-156 None
A0A7J7YS22 9-64 None
A0A2K5DDJ0 54-123 None
A0A2K5DDL0 55-138 None
A0A7E4S6M1 39-100 None
T0NMY6 17-75 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.