DPCstruct | MC12852

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)427 ± 48 aa
Standard deviation of domain lengths47.94
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score68.17
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)28.70
Pfam Score81.82
Assigned Pfam label(s) PF10267- PF15456

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q6NRH6 48-508 NLSQASSMVSSGADGMLGTDAVDGTPDPQRTKAAILQLQQKILKLTEQIKIEQTARDDNVAEYLKLANNADRQQGARIKQVFEKKNQ…
L8GBC9 19-457 APEEVDSLRKQCIRLTQRIESTRQNLAVQSKYRDAAINVGKLYSDGGDGKRRSRGSLGLKRNSHTDQSREAEAERAASEQRCEELAQ…
A0A0K0D1X8 91-477 None
A0A455AGN1 80-529 None
A0A1S3P4R3 7-395 None
A0A3Q0J6S3 147-564 None
A0A2D0RGU0 1-433 None
A0A811U8Z2 98-455 None
E0VDV9 66-571 None
A0A6J8A7A3 154-648 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.