DPCstruct | MC12840

Metacluster Properties and Pfam Annotations

Number of structural domains621
Mean domain length (aa)164 ± 25 aa
Standard deviation of domain lengths24.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score87.54
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.70
Pfam Score98.77
Assigned Pfam label(s) CL0301- CL0020- CL0037- CL0010- CL0504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3N2M2S8 1-162 MSIMGETMLDVDQMYLFVKSQNKDFPREIAEAFHRIGSAYGIRGDIALCQSILETGWFRFTGGTAVKPDQHNYCGLGVTRLGKKGHA…
A0A1F6WV62 12-138 KAEAIDAYFESRDMPLVGTGMKMVEEAEKNNLDWRLIPAIAVRESTGGKNECKKVPNNPFGWGSCKIGFKSNEEAIEVVAKNLGGNN…
A0A348N9N6 49-209 None
A0A1C6HVU7 2-163 None
A0A7V8ZFV5 120-274 None
A0A433REJ1 142-294 None
A0A255TUJ9 3-136 None
A0A1I1MIA0 27-209 None
A0A1Y3TAM3 240-402 None
T0E765 47-173 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.