DPCstruct | MC12832

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)72 ± 8 aa
Standard deviation of domain lengths7.72
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score95.63
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.96
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)53.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8XAF5 404-472 GHFISPEGEVLTEEAWRKHEFQWLPSAKDYAYVQSLMSGRVTEPGKFANWIAPPVRGINNQPLDFEYVR
A0A375IHW0 1-61 MISDAEWRDFRDQWLPTEGDRAFVASLMGRVVEPGKFANWIAPPVMGINRQPVDFEYVRFN
A0A2P9GW95 248-317 None
A0A1F7LII1 87-161 None
A0A1Q8AR79 200-270 None
A0A7W0KP82 44-130 None
A0A7W0L8V0 1-87 None
A0A534R3I2 102-175 None
A0A7Y3M6K7 16-77 None
A0A2W5ITK4 346-415 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.