DPCstruct | MC12827

Metacluster Properties and Pfam Annotations

Number of structural domains500
Mean domain length (aa)249 ± 52 aa
Standard deviation of domain lengths51.85
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score76.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)21.51
Pfam Score99.52
Assigned Pfam label(s) CL0023- CL0123- PF20209- PF14214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D3CB68 255-511 None
A0A1R3KEF6 499-794 None
A0A4S9WP07 75-339 None
A0A6S7GQ89 292-552 None
A0A179I1L0 342-553 None
A0A5S6Q5Q3 335-558 None
A0A819S9N0 256-437 None
A0A1R3ICS0 4-187 None
A0A2V1CZB0 784-1072 None
A0A819ULZ0 1-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.