DPCstruct | MC12824

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)161 ± 19 aa
Standard deviation of domain lengths18.83
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score72.01
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)42.54
Pfam Score100.00
Assigned Pfam label(s) PF14728

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G0ID59 3-163 LAEAAEENRALLEEAFVRLRSATHLLVLLLSLWQGLTPDQTTILEAMLLPLLQDTPQLGWEESCDAAVSHLLRTCLSRSPKDQATSL…
A0A0D2K5T6 150-280 VSLADEEEAAQTATRGAAQALGAGVQLLLQLISAKFGTPDEDVAVLKESLTPTVGHDDAEVGWEEEVEAGLTHLLRSALARNSKEAA…
V5H065 2-160 None
A0A2I0UDH4 32-175 None
A0A6A5FCF7 248-405 None
A0A6P4Y676 701-867 None
A0A421GQC1 513-675 None
A0A437CKL7 1033-1227 None
D8UFW5 476-633 None
H2YQG8 2-124 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.