DPCstruct | MC12821

Metacluster Properties and Pfam Annotations

Number of structural domains930
Mean domain length (aa)220 ± 41 aa
Standard deviation of domain lengths40.94
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.80
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)19.51
Pfam Score96.99
Assigned Pfam label(s) CL0023- PF00786- PF20924- PF00784- CL0184

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H0VNY4 80-224 IKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANIYPDINIITGALKLYFR…
A0A6G0I4Z0 12-244 EGRSSASTTRVFGVPLEEVTRTHTISGHEVPALVKHIVDYIEEHGHLDLEGLFLVNGNAERVDWLRQRYDSGEEVELEKEADLASAV…
F4PN41 311-539 None
F4PSG8 127-334 None
F4PUS6 621-779 None
C4M795 697-911 None
F4Q697 687-888 None
M2R7W9 112-294 None
M2RSN7 62-261 None
A0A815VEL6 76-265 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.