DPCstruct | MC12812

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)73 ± 5 aa
Standard deviation of domain lengths5.49
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.16
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)49.95
Pfam Score100.00
Assigned Pfam label(s) CL0395

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812TW41 33-111 GKLRSNFLGLEFVAYGEGMNPKKIDSSMSQVHALQLARQELLAVQYSSSLWGTKPRGPRKMGAVIPKVQPSGERMICRT
A0A6J3RYG8 1-73 MGSNLLGNRFTVFDNGQNPHRGGSTDVGSLRQELAAVIYETNVLGFRGPRRMTVIIPGMNSDKERVPIRPRNV
A0A5S6QFU7 149-224 None
B7P1A7 93-161 None
A0A2A6D368 268-335 None
M7BP62 277-347 None
A0A3L8S597 2-66 None
A0A498MD98 429-502 None
A0A182KD19 278-346 None
A0A1I8IQH2 540-619 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.