DPCstruct | MC12784

Metacluster Properties and Pfam Annotations

Number of structural domains145
Mean domain length (aa)319 ± 73 aa
Standard deviation of domain lengths72.95
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.04
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.57
Pfam Score75.42
Assigned Pfam label(s) PF13864- PF01124- CL0260- PF00621- CL0198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4T3L6 142-321 QRRITLDNHNTIITGALSLLAENAELSEEDGRGVAFRRAAAVLKALPEPVTCMTQLRGLPCLGEHSLRVIKDILENGESNEVESMKQ…
A0A0M0JTJ3 682-1008 EDEDDDMDALGPAVALAQGLSTKEFIIAEIKKLGAAYKSGAGGSGQHGSWARNQHYLQAPGAIEHHLREPVSLKTLQALRRVHGIGE…
A0A553NJN7 94-352 None
A0A1I8IBB6 81-292 None
A0A6P6QS51 57-304 None
A0A5J4YMS2 421-769 None
B8JIE9 179-564 None
A0A7S4PPF1 212-600 None
A0A1F8P1M2 3-194 None
A0A069RG09 4-242 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.