DPCstruct | MC12780

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)108 ± 13 aa
Standard deviation of domain lengths13.31
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score77.37
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)25.17
Pfam Score100.00
Assigned Pfam label(s) PF18974

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H5WP27 12-119 LRVMKKLAPNARGAKGVSAAYGGKLVCVRHRLDATGMKRLITVELIVAEKAIARRPGPTVDLSLRPQEKELQAKLKAAGAKWHESDA…
A0A0M0JR81 113-215 CPRKIVAGVRNRNVPLMCPYGEKDDVKQLGGRWNNEERQWYVPAGLELAPFSRWNAEAFTYLRFAWRDEELRSRIKAQGAEFDGKTK…
A0A7S0XLN9 74-182 None
A0A533QZM6 188-308 None
E1IET6 3-93 None
A0A7S3ZV34 500-593 None
A0A5E7QCU6 30-152 None
A0A7S3LNI9 53-148 None
A0A4R6DUH9 730-844 None
A0A2A4SQK9 1-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.