DPCstruct | MC12779

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)227 ± 39 aa
Standard deviation of domain lengths38.95
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.74
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)17.04
Pfam Score95.00
Assigned Pfam label(s) CL0724- PF18504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M0JR07 8-222 HARYETLVNLRETQPERAAAAATSALQKSRKSSEALIAALRAEIDAYKENKQLGCTASMPSDELTAARAESADLRRQLADARAKLAA…
J7S2J4 3-180 ALQEYKDSVQERLNSADLLVSKAVHENSILTERLETQERELEALRKRVAELEVDCQGAKDDRNSSVEDLQVIKDFFSHLCDVRVHSR…
A0A1Y2HV75 165-413 None
K3W6J4 1-150 None
A0A6A5Y2B1 525-769 None
A0A5C2SLQ2 63-322 None
C1EAS6 232-541 None
A0A2A9NVK0 15-252 None
A0A7S2S7C1 121-428 None
A0A0E9NBQ5 537-749 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.