DPCstruct | MC12747

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)65 ± 11 aa
Standard deviation of domain lengths11.10
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)25.84
Pfam Score100.00
Assigned Pfam label(s) PF01355

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A536YWR2 2-69 VSESEPTAVALKYKMDATKATDRKDAKALCSNCNFYTGKPGDANGPCSVFGGKLVAAKGWCASWAKKA
P00266 1-63 GTNASMRKAFNYQEVSKTAGKNCANCAQFIPGASASAAGACKVIPGDSQIQPTGYCDAYIVKK
A0A4R5QJJ2 1-45 None
A0A0R3QCK6 310-383 None
A0A0F9H3R1 40-97 None
M0MHZ2 137-194 None
C6XZ75 75-144 None
A0A063BE60 3-85 None
A0A0F9U604 23-82 None
A0A258W433 48-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.