DPCstruct | MC12739

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)69 ± 5 aa
Standard deviation of domain lengths5.22
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.63
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)44.46
Pfam Score100.00
Assigned Pfam label(s) PF08846

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A351L7N2 1-63 MFWWLEVKTKQPNCIYYFGPFDSAIEAEQGQEGYLEDLKQEGAQEIEAQIKLYSPNELTIFQD
A0A2E6GHM2 2-71 IRNFGNKLGLAWWAKVETNSPNAVYWYGPFLTKNSLKQNLNDFMRDLSDEGSNNIKHTLIRCKKTEPLTI
F5UMW4 21-85 None
B4VUI9 67-131 None
U7QI54 79-139 None
E0UIE2 17-91 None
A0A0P7Z3R1 32-108 None
A0A838VQ69 15-90 None
A0A6P0TI60 6-72 None
A0A2T1D905 4-61 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.