DPCstruct | MC12718

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)155 ± 17 aa
Standard deviation of domain lengths16.91
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.31
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)31.93
Pfam Score100.00
Assigned Pfam label(s) PF20220

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J7TP80 450-580 KQLQNQSEPCRSEALSGEYRALVMGKPLANRDDIWRTLLIDGKVSAEITTTPLADAIAGIQLYINRTVAGDEPGADNAVLERQFFKD…
A0A0B4CZX6 514-658 VPAYRHAFAELKRDALVAAYMKTKVAGDLDLTETIKDRDALYRHLLLDVDVTSAVPTSPIVEAASSLQLYISRALSGLEPEIGFYDR…
A0A1V3XST4 324-478 None
A0A3M6BBI1 624-764 None
A0A509C3A2 1-163 None
A0A0N0WPR3 1-166 None
A0A3Q9D6W4 1-168 None
A0A4D7JP61 731-871 None
A0A3M3G8N2 373-513 None
A0A4V3F8P5 1-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.