DPCstruct | MC12712

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)147 ± 9 aa
Standard deviation of domain lengths8.68
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score83.08
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)42.07
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9MAA7 1-158 MSDPHICDDKDLKELCPSLDLWLKPQAKLNITVALPRLKVLDNSGKTMTISTWEVMDKLKKKIKPLKFKTIKVSKSTIEFIRFEAEC…
A0A6A4S1X1 7-145 DTTEAVCLSTEYSLYLKPIAKITVSVALPQLKLPGKSISNWEVMERIKAMVAPEQFSALRISKSTMDFIRFEGEVENKAVVKSLLAR…
A0A183T0Y4 16-149 None
A0A4Y2L9K1 6-147 None
G4V9B3 9-155 None
A0A1A9Z8E6 17-158 None
A0A7I8VUT7 1-149 None
A0A177B2I3 21-176 None
A0A131XRH8 7-147 None
A0A3P7J3C8 1-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.