DPCstruct | MC12702

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)88 ± 7 aa
Standard deviation of domain lengths7.20
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score93.14
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)36.75
Pfam Score100.00
Assigned Pfam label(s) CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I1ISA6 53-137 IRFLRSQGWKVRYIRNITDIDDKIIKRANENGETIQQLTTRFIDAMNEDAANLGCLAPDEAPKATEYIDQMQNMIGNLVNKGAAY
A0A6V8P1V9 52-138 RRYLLYKGYQVLFVQNITDVEDKIINKARQLGLGWQEVAQKFEREFYQDMEKLGIMPADVQPRATEQIDFMIKMISTLEEKGYAYDG
A0A0G0VWE4 51-152 None
A0A0G1NX16 9-110 None
M1V4Z4 56-150 None
A0A452VAS0 45-136 None
A0A5J4YNC0 73-159 None
A0A554J927 54-137 None
A0A0B2Q600 22-107 None
A0A4R0XMV7 288-380 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.