DPCstruct | MC12686

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)116 ± 10 aa
Standard deviation of domain lengths9.80
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score83.20
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)27.79
Pfam Score60.00
Assigned Pfam label(s) CL0459- PF11411

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067KY67 1-114 MVIENGGTFSMNLNKSVTHCIAAENKGIKYQAAKLHGDVIHCSWVLDCCSQKKLLPLQPKYFLFLSEASKKKLQEEIDEFSDSYYWD…
A0A287J6P4 105-221 VVENGGSFSMNLNDSVTHCIAAEKKGIKYQAAIRHGRIIHYSWILDCCKQKLLLRLQPKYILFLADFARHKFPEEIDLYADFYYWDI…
A0A507DAE0 462-598 None
A0A507CZ80 199-297 None
A0A2W1BSD6 358-477 None
A0A6A1Q7S2 434-550 None
A0A3M6VHF6 261-395 None
A0A5J5NR53 156-268 None
A0A059CKF0 281-393 None
A0A3M7BW31 289-405 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.