DPCstruct | MC12671

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)398 ± 67 aa
Standard deviation of domain lengths66.81
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.65
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)23.83
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q9DAP2 11-339 DDKRNLSSLAEKLNEIANRLGTDASPEAVGQALASTTLQARPESSITLEAFIQGNGLGLPTCHFHLVSLAAAVGDRALQHPLGSFGG…
A0A1H0Z101 10-438 QHHAGQLAEYDSLLSQLRKIPTSGIRTDNTYLTPKPFSPLAREFDKGSAHIAEVVQSIGAEVRPDRLLCLTHILKYYGLTVPEHQDA…
A0A3R8W7P1 17-353 None
A0A7T4REU1 2-384 None
A0A0J6INC8 2-330 None
A0A4Y9TDV0 8-358 None
A0A2G0XB50 166-602 None
A0A2G0XBN7 2-345 None
A0A7Y8KGU4 2-309 None
A0A2K4IHE8 10-347 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.