DPCstruct | MC12659

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)93 ± 3 aa
Standard deviation of domain lengths2.89
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score82.83
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)50.36
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3E0M535 1-97 MFRDFKSGGYSLEGSQLAPQYLSKLIIVIAIAYTSATLQGKKIKDMGIQKYVTRPEKRYKGQRRHSSFYVGQHLYHWLQLHQMFQKN…
A0A6M0CFW3 75-165 MGIEEMFRDFKNGGYNKEGTQVKGERLISLTLLITLAYCQSTIVGGKIVKKGVANYVNRPTEKPRKYRRHSHFYTGNRGETWLNGLE…
Q10YJ5 1-93 None
D8FYX8 9-98 None
F4Y321 94-185 None
L7E7S0 1-94 None
A0A0A1VWX1 72-168 None
A0A845WNH8 115-205 None
L8NR56 1-94 None
A0A5A5RAT3 35-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.