DPCstruct | MC12649

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)123 ± 11 aa
Standard deviation of domain lengths10.69
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score74.21
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)35.67
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2Y1R1 1-109 MSPDKIFLRQWTVSLLEAAMADLALEMERIGKMQLFAILRPLLELDGEHGQQEKDAQAAGMSYSAFRVALTRLRRRFGVIIREKVAD…
A0A7W1JBI0 4-119 AVVDPAAPAVPDPAFDRDWADVLLARAGDRLAAEHATPGERARYERLAHFVTTNGTSASYAAAGALLGLTEGAVKVAVHRLRQRLRD…
A0A645IKZ2 24-143 None
A0A150PW44 6-115 None
A0A1G3A5C2 56-174 None
A0A354T872 21-132 None
A0A1W9LH84 42-158 None
A0A522S1B8 318-460 None
A0A3E0NNK1 319-451 None
A0A7C3HGZ3 83-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.