DPCstruct | MC12640

Metacluster Properties and Pfam Annotations

Number of structural domains99
Mean domain length (aa)205 ± 45 aa
Standard deviation of domain lengths44.71
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.66
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)25.16
Pfam Score0.00
Assigned Pfam label(s) CL0031- PF10187- CL0027- PF12017

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4VIV0 186-407 RLARGVHGGKLLDDSDAHRQIGPINHARWLTLATRLLRVYIGSPSPTAELTELVEFLMGHYIPMWFHIRANSTCTSGALNVMRSIEL…
A0A5N4B741 10-243 VDEKLSKRSPGKMVHSRWLTTANRILRLYVSTDEPSENLVILVTFILKVYAPMWFIIKSKPSCLQGAFNVWKMIQLSRYLPKNLKDV…
T1FBS3 56-309 None
A0A4Y2A7E7 11-172 None
A0A4Y2A5P9 22-181 None
A0A6S7IJJ8 182-482 None
A0A4C1U6C0 300-505 None
A0A4Y2CM25 47-218 None
A0A4Y2CH24 20-228 None
A0A4Y2URE4 3-130 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.