DPCstruct | MC12626

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)263 ± 21 aa
Standard deviation of domain lengths20.74
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score80.34
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)39.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2L0A448 3-243 RISKELEKKRSHPDRLHPELWFNDPGEMNDGPLCRCSLKAQRSGIRHGYYVGEDNLNKCDPWTNNADRLHHYLITISPPTNFLIKTP…
A0A1S4ERE9 1-228 CSHCASNPTVSSGSESSSDSSSGEEDAEEDNWMMELQLKQNHPDRLHPELWFNDKGEMNDGPLCRCSSKSRRSGIRHNIYAGEDEQA…
A0A1D2N843 701-975 None
T1GFQ1 187-405 None
A0A7M5WV07 263-541 None
A0A813YRP9 246-513 None
A0A182G549 319-581 None
A0A183A920 43-337 None
A0A7R8ZDZ4 170-429 None
A0A821TE47 276-549 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.