DPCstruct | MC12598

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)59 ± 3 aa
Standard deviation of domain lengths2.50
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score82.33
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)63.73
Pfam Score100.00
Assigned Pfam label(s) CL0022

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9N0S0 1-56 MVHITEDLIRRRAEHNECEIFSLEEVTLHQQDLEGIEHIERWCKELKILYLQNNLI
A0A1S3DD24 2-60 VRISEDLVRKRAEHNDKEIGTLEEIALHQEHIEKIEALDKWCKHLRILLLHSNIISKLA
K8F2N9 4-63 None
A0A177B224 1-59 None
A0A6A4WKG2 232-295 None
A0A5K3FHJ1 1-59 None
A0A7J7KM76 1-59 None
A0A7E6FHM8 714-778 None
A0A2C6KVX7 1-61 None
A0A7R9HKP4 8-62 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.