DPCstruct | MC12594

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)136 ± 16 aa
Standard deviation of domain lengths16.48
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score78.01
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)30.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9LSY6 708-863 GPKTPVPVTNLLIEKPRPFSCIRPLTQHNVYSYYLPLNGCVSYYAFSLHSSLPGGLFRLLPNSGVRVVNCLLFNSHIGIGVYLYMSR…
A0A1S3D0X6 17-152 IKPFNQQNVMYYYAPIYGATNYALLSVNVMHPSLMYRIIPKHDVANVFLFTSVIGSGLYIHGRKHLQGAPQQLQVMFSAYGSLLFSF…
A0A2B4SUJ8 29-193 None
A0A5N4A577 6-145 None
A0A182W9D7 10-152 None
A0A0N5ASZ3 1-125 None
J9EZA6 6-158 None
A0A1J1J7A9 6-136 None
A0A212EV77 3-115 None
A0A182Y217 62-197 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.