DPCstruct | MC12566

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)144 ± 15 aa
Standard deviation of domain lengths15.15
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score88.70
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)31.46
Pfam Score100.00
Assigned Pfam label(s) CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A380EEG5 4-142 NERIEKGYQAFVKDDYTQVLNTYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELGQGHLDEAI…
T0TBK1 18-157 KNAVIDAQAAFMSTDYDKAIDILEPYGINRLPKSAKYVLATSFVKLDNLNSEQMEAVLNTITQSSDETILNYWIYLGRGDLEKALDV…
A0A0A5GD23 247-393 None
R3KK15 165-298 None
W7C4S1 186-333 None
A0A5R8LX43 1-112 None
A0A2C1KG57 173-323 None
I0R8M8 2-123 None
R6PXC0 72-219 None
Q7A1V2 228-394 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.