DPCstruct | MC12559

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)189 ± 48 aa
Standard deviation of domain lengths48.20
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score83.31
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)37.85
Pfam Score97.50
Assigned Pfam label(s) CL0020- PF12807

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453FK54 197-352 EVALPKLVADFGSLELSPVDGRTLTDFMHTRGLQMRSLGRVVKLSEKLSHVQSLCVHEMIVRAFKHIVQSVIAATSDMRQLALTIAA…
A0A453D8K5 2-161 YDDTALPKLVADFASLELSPVDGRTMTDFMHTRGLNMCSLGRVVELAEKLPHIQSICIHEMVIRAFKHVIRAVIAAVDDMQNMSAVI…
A0A453FKA4 10-170 None
A0A453PF02 134-306 None
A0A0K0E7J3 1419-1601 None
E7FE02 1068-1370 None
A0A7J0G7M0 565-726 None
A0A3Q1EZR2 704-983 None
F4PP85 770-1007 None
A0A7S3GK75 883-1044 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.