DPCstruct | MC12550

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)122 ± 11 aa
Standard deviation of domain lengths11.04
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score80.36
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)31.90
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J1W6M0 66-201 MDSLLKKYQPVSPVDAQPHWESSYDFSLKHCNHAVWNRNCKVVQEGKECFQGARLRHYYMLCGALLRVWTKIASIMANITNTSYLQI…
A0A453CSC3 5-121 SELKGKYRKVSSIDKVSKGWQDEYDVSSKQCMHGSKCKVGSYCTVGRRLQEFNILGGLILPVWGTIEKALAKQVYQNHKRIRVVRLV…
A0A812EQ48 96-216 None
A0A7R8WF20 350-482 None
A0A7J7XL06 712-841 None
A0A383VFB9 631-759 None
E9HLM0 493-598 None
A0A6J1PZ46 450-566 None
A0A3P7J1W2 1-123 None
A0A3L6VME2 157-279 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.