DPCstruct | MC12528

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)189 ± 40 aa
Standard deviation of domain lengths39.88
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score75.77
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C2X8T2 36-206 YVKARPGVDIDLDDHKCFSLRYVAHVDDGAGAGPLSYPNKDKLLHANIPVKILVPHITLKAVRDIAKIHGIALDRKAQDKRERICEL…
A0A836XLI0 119-278 VNKVGLIFHGVYSDIEVLQYPASVYLHVKADVTIILPLLSARECISVALKHGIVCGSKCTKSLIISMSQDHSCAICYSLTYVFEVKN…
A0A409X9T4 10-255 None
A0A836DAV5 66-231 None
A0A284RDJ5 9-179 None
A0A284RAN5 60-215 None
A0A0C3JB76 1-237 None
A0A067TAZ2 540-690 None
A0A067T1D6 10-169 None
A8P9I4 112-303 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.