DPCstruct | MC12497

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)354 ± 19 aa
Standard deviation of domain lengths19.40
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score79.14
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)29.17
Pfam Score93.75
Assigned Pfam label(s) CL0220- CL0125- PF16648- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P7SXH5 380-748 VYEDDGEFWMSFQDFVSNFQKLEICNLAPDSLDEDELNARSKKRWESTCESGSWVKRVSAGGCRNYLDTFWTNPQFKVSLTDPDDDD…
A0A210QM44 704-1062 IVVRNDGEFWMSYHDLLLNFDEVQLCHLQPDALTSEIVNDEKQEAWQVVVYHDAWLKGVTAGGCGNKPHQDLYWRNPQFFITLKDVD…
A0A836CV14 327-688 None
A0A7R9JXE5 398-722 None
A0A662YND4 282-601 None
A0A210QPN2 589-968 None
A0A4Z2HVP4 726-1090 None
A0A4Z2AYD2 109-478 None
A0A7I8VY88 732-1086 None
A0A6F8ZK98 77-410 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.