DPCstruct | MC12490

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)76 ± 15 aa
Standard deviation of domain lengths14.77
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)53.55
Pfam Score100.00
Assigned Pfam label(s) PF02238

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4SEJ8 11-71 VARRAFSSSAGQLRNRIREAQKLFQEDNGLPVHLKGGSRDVLLYRATMTLTLAASMPQKKA
A0A3B4BY52 1-60 MRNKVPEKQKIFQEDNGLPVHIKGGTTDVLLYRLTMSLTIAGTGFSCYWLLVASMPRSKA
A0A287CYE4 6-71 None
A0A2D0PXK3 37-119 None
H3AAH4 25-102 None
A0A3B3Q7F4 1-66 None
I3MIU4 29-115 None
A0A3Q2XXS1 61-141 None
G5AMW5 147-269 None
A0A673YB69 4-63 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.