DPCstruct | MC12488

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)141 ± 17 aa
Standard deviation of domain lengths17.39
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score87.78
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)43.86
Pfam Score98.33
Assigned Pfam label(s) PF08337- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3A2E1 298-414 FWINILKNPQFIFDIEKTPHLDSCLSVIAQAFMDAFSLTDHQLGKHAPTNKLLYAKDIPQFKEEVKAYYKQIQELPSLSSQEVEEFL…
A0A6A4SBK2 2-145 RFWVNILRNPHFIFDVHVTEVVDASLHVISQTFMDACTKTEHKLSRESPSNKLLYAKEISTYKKNVDDYYRGIRQMVPVSDQDMNTH…
A0A2H2I224 75-223 None
A0A3B3QIQ7 242-389 None
A0A5J5CEK7 579-732 None
A0A0K0E5W4 2-145 None
A0A2B4SHF4 653-799 None
A0A7R8X038 833-978 None
T1H2W6 1-115 None
T1FRH1 537-686 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.