DPCstruct | MC12472

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)118 ± 18 aa
Standard deviation of domain lengths18.15
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score71.92
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)50.60
Pfam Score71.58
Assigned Pfam label(s) PF16543- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z6QZJ8 1-102 MDKWDQEKLEQVVKSKQGNPKTTTDIVCKYFLEAIENQKYGWFWECPNGGKKCMYRHALPPGFVLKTKAQKKAEEEGEDQITIEEFL…
A0A0S7HE53 11-125 YVDERDEDLEKDTMENWDEKKLEEVVNKKHGEAEKKKAKTQIVCKYFLEAIENNKYGWFWVCPAGGDNCMYRHALPPGFVLKKDKKK…
A0A2I0HL54 117-237 None
A0A3P7J2G7 30-195 None
G0QLW9 125-246 None
A0A453FVK3 21-117 None
S6B750 117-231 None
Q38M61 1-92 None
A0A1A9A205 181-331 None
A0A061FUK3 2-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.