DPCstruct | MC12456

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)94 ± 7 aa
Standard deviation of domain lengths7.11
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score89.48
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)48.72
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B8NX86 1-94 MVEWRISIYGRSIQEWDKLAAWVVDNKLFSPNVRWLVQIPRLYDVYKSSGMMENFEQVITNVFQPLFEVTKDPNSHPKLHLFLQRVV…
A0A819UAK8 429-513 AEFHMSIQGRSMDEWDKLAKWFLKNEIHSTNVSYMIQVPRIFTTHRASSKLKNIEELLTNLFQPLFDATIHPESHPDLFRFMRYF
A0A6L5CH67 256-346 None
A4HVM6 1268-1357 None
A4HS23 1235-1326 None
H8ZDC3 250-350 None
A0A445B6A3 94-187 None
A0A668AM50 323-414 None
A0A086JZI8 219-313 None
J9BIV8 62-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.