DPCstruct | MC12453

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)133 ± 20 aa
Standard deviation of domain lengths20.05
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.13
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)35.72
Pfam Score95.00
Assigned Pfam label(s) PF00177- CL0020- CL0613

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L1IY42 6-133 MQLLRSAMKKDPKSYLDELFLQMRHFEANVNIFKSKPSKPMHDLQETAALLAHVTPCYPRELASFPSQLVGLLEQFHLVMDPGLRKE…
A0A819SSJ3 2-111 PGNDRLTRSLPHLQNLIKRDPDAYREDFKLQYLHFESQFMELTAKPDIWNKSLAENISFVSQVAHCYPEESKGLSQMFMDVLRLYST…
A0A194QBG7 2-139 None
A0A5J9SPK2 10-132 None
A0A812I3Y3 312-449 None
A0A835R6H6 315-451 None
A0A2B4S8Q8 1-122 None
A0A6I9JR07 2-111 None
M1A0M1 4-200 None
A0A5A7T0H3 3-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.