DPCstruct | MC12437

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)96 ± 22 aa
Standard deviation of domain lengths21.94
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score68.47
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)56.57
Pfam Score100.00
Assigned Pfam label(s) PF15129

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P7LWB4 28-124 NRINRYRSRTETAAGTEHGVKPLEREKRSHQGMDGDKDPRYKEKFIQHLTGPLSFHPKCRKQFNRIYHSTRDCTTPAYYRRCAVLLV…
A0A2K6TMI1 1-73 GPAPEQRVEIVARDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPVCME
A0A3Q2L2L8 474-576 None
A0A6I9JMY1 34-167 None
A0A286XDR0 156-255 None
A0A3Q2Y8W1 1-89 None
A0A7N9CB98 177-282 None
A0A493U3Z6 378-477 None
A0A3P9M6F7 121-208 None
A0A3P8NT28 34-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.