DPCstruct | MC12435

Metacluster Properties and Pfam Annotations

Number of structural domains183
Mean domain length (aa)132 ± 22 aa
Standard deviation of domain lengths21.63
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score74.83
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.24
Pfam Score96.87
Assigned Pfam label(s) CL0055- PF11918- PF02271- PF04709- CL0333

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A674JK95 298-435 None
A0A4Y2PEB7 341-498 None
A0A498N6K1 231-362 None
A0A653C3V4 168-282 None
A0A672GDF9 209-320 None
A0A6F9CDD6 136-288 None
A0A6P8TE34 44-198 None
A0A6P7NPP6 242-389 None
A0A3M0J5D7 264-387 None
A0A0B6VLI6 248-377 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.