DPCstruct | MC12435

Metacluster Properties and Pfam Annotations

Number of structural domains183
Mean domain length (aa)132 ± 22 aa
Standard deviation of domain lengths21.63
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score74.83
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.24
Pfam Score96.87
Assigned Pfam label(s) CL0055- PF11918- PF02271- PF04709- CL0333

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A077Z3B3 365-484 None
A0A1V4KDX9 837-957 None
F7A1Y1 809-928 None
A0A1A6FYK9 284-425 None
A0A0M3JB42 12-99 None
A0A6J2LT13 86-230 None
L9LAQ0 317-444 None
A0A1I8JSB8 173-300 None
A0A6P8GVX0 119-276 None
A0A6V7UYA0 380-492 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.