DPCstruct | MC12435

Metacluster Properties and Pfam Annotations

Number of structural domains183
Mean domain length (aa)132 ± 22 aa
Standard deviation of domain lengths21.63
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score74.83
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.24
Pfam Score96.87
Assigned Pfam label(s) CL0055- PF11918- PF02271- PF04709- CL0333

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P7ZH43 293-405 None
A0A3Q2QUK3 159-325 None
E0VEJ8 475-590 None
A0A816P3I4 464-596 None
A0A815EA22 387-510 None
A0A6G1Q8T7 122-296 None
H2Z9U2 518-670 None
A0A667WDQ4 9-124 None
A0A653CSZ2 54-206 None
A0A0R6KNR6 508-620 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.