DPCstruct | MC12435

Metacluster Properties and Pfam Annotations

Number of structural domains183
Mean domain length (aa)132 ± 22 aa
Standard deviation of domain lengths21.63
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score74.83
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.24
Pfam Score96.87
Assigned Pfam label(s) CL0055- PF11918- PF02271- PF04709- CL0333

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J5YWA7 1-95 MHVDFNQIGWGSWIIFPKRYNAYRCEGPCPGPLGEHLNPTNHAYMQSLLKHYHPDKVGSPCCAPTKMSPLSMLYYENGEMLLRHHED…
A0A6P3IZ89 27-167 KEFTEKDPSLLLRRARQAGSIASEVPGPSREHDGPESNLCSLHPFQVSFQQLGWDHWIIAPHLYTPNYCKGVCPRVLHYGLNSPNHA…
B0ZE98 22-157 None
A0A7R9NZL2 267-407 None
R7TVW3 1-136 None
A0A482WJ53 204-314 None
A0A5J5CMN4 260-357 None
A0A5J5CH14 478-582 None
A0A3G1PW81 363-466 None
A0A2C9JVU1 235-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.